This unique and complimentary assessment can be incredibly beneficial to the planning of your project, with no strings attached.
Within a few shorts weeks after the execution of a mutual non-disclosure agreement (NDA) and receipt of a small amount of your API, Corealis will deliver a comprehensive formulation and clinical supplies manufacturing development plan, designed to optimize the progress of your preclinical compounds.
Your cost-free finished assessment will also contain:
• A preliminary API characterization (if needed)
• Budget and timeline expectations
• API requirements needed for your project
• Our recommendations for your targeted therapeutic application
Required information to initiate the assessment
To conduct a thorough assessment, Corealis will require all available information regarding your API, including any toxicology data. Based on the information provided, we will evaluate the physicochemical properties of your API for:
- Particle morphology
- Particle size and size distribution
- Hygroscopicity from 10-90% relative humidity
- Bulk and tap density/flow properties
- Crystal state evaluation and stress tests
- Suitability tests for solid dosage form manufacturing
- Thermal analysis
- Forced degredation
- Solubility in SGF, FaSSIF and FeSSIF
- Solubility in water
Reduce Your Risk With Corealis
Maximize your efficiency
Make sure your API is “druggable” beforehand and get a well-defined development plan.
Ensure product integrity
Learn which product formulation is aligned with the desired absorption profile.
Communication that delivers results
Get expedited progress from proof-of-concept to characterization.
Choose Corealis as your trusted partner
Since 2005, Corealis has specialized in pharmaceutical oral solid dosage form development and Phase I/II and early Phase III clinical supply manufacturing. With all services done in-house, we ensure expertly curated solutions, accurate and rapid timelines and strong communication.
Our approach is reinforced by our:
• Reliability
• Flexibility
• Quality
• Regulatory compliance
• Personalized service
Laval, Quebec, Canada
H7V 4A6
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